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Notice to Readers: Shortage of Spectinomycin
In April 2001, Pharmacia Corporation (Peapack, New Jersey) announced it
was discontinuing U.S. production of spectinomycin
(Trobicin®)* because of low sales volume; remaining spectinomycin inventory will expire on June 30, 2001. No
other pharmaceutical company manufactures or sells spectinomycin in the United States.
CDC recommends treating patients infected with
Neisseria gonorrhoeae who have contraindications to cephalosporins and fluoroquinolones with spectinomycin
(1).Patients in this category include: 1) pregnant women with documented
cephalosporin allergies (fluoroquinolones are contraindicated in pregnancy); and 2) patients
with documented cephalosporin allergies who acquired gonorrhea infection in areas
where
fluoroquinolone-resistant N. gonorrhoeae is endemic (e.g., Asia, Hawaii, and
otherPacific Islands) (2).
For access to spectinomycin until June 30, contact Wendy
Johnson,Pharmacia Corporation, telephone (800) 976-7741, ext. 30110 or fax (800) 852-6421. In
response to this shortage, CDC and the Food and Drug Administration are working
with Pharmacia Corporation to identify a solution. Interim alternative
treatment recommendations are available at http://www.cdc.gov/std/specshortage.htm
or
from CDC's Fax Information System (888) 232-3299 ([888] CDC-FAXX), by
entering document number 210100.
*Use of trade names is for identification only and does not imply endorsement by CDC
or the U.S. Department of Health and Human Services.
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