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Persons using assistive technology might not be able to fully access information in this file. For assistance, please send e-mail to: [email protected]. Type 508 Accommodation and the title of the report in the subject line of e-mail. Notice to Readers: Request for Information About Acute Encephalopathy Associated with Influenza Virus Infection in U.S. ChildrenSince the mid-1990s, several hundred cases of acute encephalopathy have been reported in Japanese children with influenza virus infection (1,2). These cases have been characterized by fever and rapid onset of encephalopathy, resulting in a high frequency of neurologic sequelae and mortality. The majority of the children have had laboratory-confirmed evidence of influenza. Reports of influenza-associated encephalopathy have been uncommon in the United States (3,4). To determine if a similar pattern is occurring in the United States, CDC is requesting information on any case meeting certain criteria. The criteria include a person aged <18 years with altered mental status or personality change lasting >24 hours and occurring within 5 days of onset of an acute febrile respiratory illness, laboratory or rapid diagnostic test evidence of acute influenza virus infection associated with the respiratory illness, and diagnosis of the condition in the United States. Cases meeting these criteria should be reported to CDC (telephone, 404-639-0277 or 404-639-2893; fax, 404-639-3866; or e-mail, [email protected] or [email protected]). References
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This page last reviewed 12/11/2003
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