Key points
- CDC recommends diphtheria vaccines for people across the lifespan.
- Follow the recommended immunization schedule to ensure that your patients get the diphtheria vaccines that they need.
Background
The United States uses three types of combination vaccines that include protection against diphtheria: DTaP, Tdap, and Td. DT vaccine is no longer available in the United States.
DTaP and Tdap also include protection against tetanus and pertussis. Td also includes protection against tetanus. Children younger than 7 years of age receive DTaP, while older children and adults receive Tdap or Td.
The following summarizes CDC's current age-based recommendations for DTaP, Tdap, and Td. Access the official, full text of CDC's current and historical DTaP/Tdap/Td vaccine recommendations.
Infants and children
CDC recommends routine DTaP vaccination for all infants and children younger than 7 years old.
Administer a 5-dose DTaP series, 1 dose at each of the following ages:
- 2 months
- 4 months
- 6 months
- 15 through 18 months
- 4 through 6 years
Adolescents
CDC recommends routine Tdap vaccination for all adolescents.
Administer a single dose of Tdap at 11 to 12 years of age.
Catch-up guidance
Vaccinate children who miss their shots or start the series later than recommended. Depending on the child's age when vaccination begins, the recommendation varies for
- Type of vaccine
- Number of doses
- Interval between doses
Job aids for simplifying catch-up guidance
Use the following job aids to help interpret table 2 of the child and adolescent immunization schedule.
Adults
CDC recommends vaccination every 10 years for all adults to maintain protection against diphtheria. Once an adult has received a dose of Tdap, administer Td or Tdap for their booster doses.
Patients with a contraindication
A history of a severe allergic reaction (anaphylaxis) to a vaccine component or following a prior dose is a contraindication to further doses.
For patients with a contraindication specific to pertussis-containing vaccines, follow these age-based recommendations:
Children <7 years of age: See About young children with a contraindication to pertussis-containing vaccines.
Persons ≥7 years of age: Use Td instead of Tdap.
Find more resources below about contraindications.
Resources
Contraindications and precautions
General Best Practice Guidelines for Immunization
Pink Book chapter on
Immunization schedules
Child and adolescent immunization schedule
Vaccine Information Statements
DTaP: English | Other languages
Tdap: English | Other languages
Td: English | Other languages