Persons using assistive technology might not be able to fully access information in this file. For assistance, please send e-mail to: [email protected]. Type 508 Accommodation and the title of the report in the subject line of e-mail.
Update: Severe Acute Respiratory Syndrome --- United States, 2003
CDC, in collaboration with state and local health departments, the World Health Organization (WHO), and
other partners, continues to investigate cases of severe acute respiratory syndrome (SARS). During November 1, 2002--May 7, 2003, a total of 6,903 SARS cases were reported to WHO from 29 countries, including the United States; 495 deaths (case-fatality proportion: 7.2%) have been reported
(1). This report updates information on reported U.S. SARS cases.
As of May 7, a total of 328 SARS cases in the United States have been reported from 38 states, of which 265 (81%)
were classified as suspect SARS, and 63 (19%) were classified as probable SARS (more severe illnesses characterized by the presence of pneumonia or acute respiratory distress syndrome) (Figure 1,
Table)
(2). Of the 63 probable SARS patients, 42 (67%)
were hospitalized, and three (5%) required mechanical ventilation. No SARS-related deaths have been reported in the
United States.
Laboratory testing to evaluate infection with the
SARS-associated coronavirus (SARS-CoV) has been completed for
69 cases. Six cases of laboratory-confirmed infection with SARS-CoV have been identified; all were probable cases, as
described previously (3,4). No new SARS-CoV confirmed cases have been identified since the last update. Negative findings (i.e., the absence of antibody to SARS-CoV in convalescent serum obtained >21 days after symptom onset) have been documented
for 63 cases (49 suspect and 14 probable).
Of the 63 probable SARS patients, one (2%) was a health-care worker who provided care to a SARS patient, and one (2%) was a household contact of a SARS patient
(5). The remaining 61 (97%) probable SARS patients had traveled to areas
with documented or suspected community transmission
of SARS during the 10 days before illness onset
(2). Among the probable SARS patients with travel exposure, 36 (59%) had traveled to mainland China; 19 (31%) to Hong Kong Special Administrative Region, China; five (8%) to Singapore; three (5%) to Hanoi, Vietnam; and seven (12%) to Toronto,
Canada (Figure 2). Eight (13%) probable patients had visited two or more areas with SARS during the 10 days before illness onset. Of the six probable SARS patients with positive SARS-CoV laboratory results, two had traveled to Hong Kong; one to Hong Kong and Thailand; one to Hong Kong and Guangdong, China; one to Singapore; and one to Toronto.
Since the last update (6), the epidemiology of SARS in the United States has not changed markedly; the majority of
cases continue to be associated with travel and secondary spread to contacts (e.g., family members and health-care workers) is limited. However, the collection and testing of convalescent serum is an ongoing priority to precisely characterize
the epidemiology of SARS in the United States and worldwide.
Reported by: State and local health departments. SARS Investigative Team, CDC.
Use of trade names and commercial sources is for identification only and does not imply endorsement by the U.S. Department of
Health and Human Services.References to non-CDC sites on the Internet are
provided as a service to MMWR readers and do not constitute or imply
endorsement of these organizations or their programs by CDC or the U.S.
Department of Health and Human Services. CDC is not responsible for the content
of pages found at these sites. URL addresses listed in MMWR were current as of
the date of publication.
Disclaimer
All MMWR HTML versions of articles are electronic conversions from ASCII text
into HTML. This conversion may have resulted in character translation or format errors in the HTML version.
Users should not rely on this HTML document, but are referred to the electronic PDF version and/or
the original MMWR paper copy for the official text, figures, and tables.
An original paper copy of this issue can be obtained from the Superintendent of Documents,
U.S. Government Printing Office (GPO), Washington, DC 20402-9371; telephone: (202) 512-1800.
Contact GPO for current prices.
**Questions or messages regarding errors in formatting should be addressed to
[email protected].
